Article

Abstract

• We report the liquid crystal (LC) ordering in an aqueous solution of four-base-long DNA oligomers 5′-GCTA-3′. In such systems, the formation of the chiral nematic (N*) LC phase is the result of a continuous self-assembly process in which double helix stability is achieved only through linear chaining of multiple DNA strands. The thermal stability of the aggregates and their LC phase diagram have been experimentally investigated, quantitatively interpreted with theoretical models and compared with recent results on four-base sequences with only G-C or only A-T pairing motifs. N* phase is found at GCTA concentration, cDNA, between 240 and 480 mg/mL and at temperature T < 30 °C. The twist of the nematic director is found to be left-handed with pitch (p) in the optical range, increasing with cDNA and decreasing with T.

Creator

• Fraccia, Tommaso P.
• Clark, Noel A
• Smith, Gregory P.
• Bellini, Tommaso

Date Issued

• 2017-12-01

Academic Affiliation

• Physics

Journal Title

• Crystals

Journal Issue/Number

• 1

Journal Volume

• 8

最新修改

• 2019-12-05

Resource Type

• Article

权利声明

• In Copyright

DOI

•  https://dx.doi.org/10.3390/cryst8010005

ISSN

• 2073-4352

Language

• English [eng]

License

• Creative Commons BY Attribution 4.0 International

关联

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	liquidCrystalOrderingOfFourBaseLongDnaOligomersWithBoth.pdf	2019-12-05	公开	下载
	liquidCrystalOrderingOfFourBaseLongDnaOligomersWithBoth.pdf	2019-12-05	公开	下载