During the past few years the attention of many investigators has been directed to the determination of the absolute hemoglobin content and volume of human red blood cells. This interest has been stimulated by the application of the procedure to the diagnosis and prognosis of anemias, and to observations of the blood response to therapeutic measures.
Andresen, Marjory Irene, "The Mean Corpuscular Volume, Corpuscular Hemoglobin and Corpuscular Hemoglobin Concentration of Infant, Child and Adult Blood" (1934). University Libraries Digitized Theses 189x-20xx. 60.