Document Type
Article
Publication Date
6-6-2015
Publication Title
Environmental health : a global access science source
ISSN
1476-069X
Volume
14
First Page
49
Last Page
49
DOI
https://doi.org/10.1186/s12940-015-0037-4
PubMed ID
26047618
Abstract
BACKGROUND: Associations of short-term exposure to fine particulate matter (PM2.5) with daily mortality may be due to specific PM2.5 chemical components. Daily concentrations of PM2.5 components were measured over five years in Denver to investigate whether specific PM2.5 components are associated with daily mortality.
METHODS: Daily counts of total and cause-specific deaths were obtained for the 5-county Denver metropolitan region from 2003 through 2007. Daily 24-hour concentrations of PM2.5, elemental carbon (EC), organic carbon (OC), sulfate and nitrate were measured at a central residential monitoring site. Using generalized additive models, we estimated relative risks (RRs) of daily death counts for daily PM2.5 and four PM2.5 component concentrations at single and distributed lags between the current and three previous days, while controlling for longer-term time trend and meteorology.
RESULTS: RR of total non-accidental mortality for an inter-quartile increase of 4.55 μg/m(3) in PM2.5 distributed over 4 days was 1.012 (95 % confidence interval: 0.999, 1.025); RRs for EC and OC were larger (1.024 [1.005, 1.043] and 1.020 [1.000, 1.040] for 0.33 and 1.67 μg/m(3) increases, respectively) than those for sulfate and nitrate. We generally did not observe associations with cardiovascular and respiratory mortality except for associations with ischemic heart disease mortality at lags 3 and 0-3 depending on the component. In addition, there were associations with cancer mortality, particularly for EC and OC, possibly reflecting advanced deaths of a frail population.
CONCLUSIONS: PM2.5 components possibly from combustion-related sources are more strongly associated with daily mortality than are secondary inorganic aerosols.
Recommended Citation
Kim, Sun-Young; Dutton, Steven J; Sheppard, Lianne; Hannigan, Michael P; Miller, Shelly L; Milford, Jana B; Peel, Jennifer L; and Vedal, Sverre, "The short-term association of selected components of fine particulate matter and mortality in the Denver Aerosol Sources and Health (DASH) study." (2015). Mechanical Engineering Faculty Contributions. 75.
https://scholar.colorado.edu/mcen_facpapers/75
Comments
See attached file for erratum.