To survive challenging environments, animals acquired the ability to evaluate food quality in the intestine and respond to nutrient deficiencies with changes in food-response behavior, metabolism and development. However, the regulatory mechanisms underlying intestinal sensing of specific nutrients, especially micronutrients such as vitamins, and the connections to downstream physiological responses in animals remain underexplored. We have established a system to analyze the intestinal response to vitamin B
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Qi, Bin; Kniazeva, Marina; and Han, Min, "A vitamin-B2-sensing mechanism that regulates gut protease activity to impact animal's food behavior and growth." (2017). Molecular, Cellular, and Developmental Biology Faculty Contributions. 48.