Date of Award

Spring 1-1-2014

Document Type


Degree Name

Master of Science (MS)


Integrative Physiology

First Advisor

Marissa A. Ehringer

Second Advisor

Thomas E. Johnson

Third Advisor

Charles A. Hoeffer

Fourth Advisor

Jerry A. Stitzel


In the U.S., where nicotine is the most prevalent form of addiction, there are roughly 443,000 smoking related deaths per year and an additional 16 million who suffer from smoking related illness. Our lab has shown that exercise reduces alcohol consumption in mice. This study looked at the effect of exercise on nicotine consumption in adult mice. While the pilot study showed evidence for hedonic substitution, the main study had no significant results. Further research is needed to determine the effect of exercise on nicotine consumption.