Type of Thesis
This work describes the total synthesis and characterization of an asymmetrically substituted scyllo-inositol. Starting from a cheap an abundant α-D-methylglucoside, generation of the product was achieved in nine steps. This synthesis capitalized on a Ferrier II reaction which generated the inositol core, followed by a selective reduction, protection, and stereochemical inversion to convert the initial myo-inositol to the desired scyllo-inositol. This asymmetric scyllo-inositol will be used in the future as the head of axinelloside A.
Rodriguez, Jacob, "SYNTHESIS OF ASYMMETRICALLY SUBSTITUTED SCYLLO-INOSITOL" (2018). Undergraduate Honors Theses. 1600.