Document Type

Article

Publication Date

3-20-2017

Publication Title

Optics Express

ISSN

1094-4087

Volume

25

Issue

6

First Page

6122

Last Page

6131

DOI

http://dx.doi.org/10.1364/OE.25.006122

PubMed ID

28380967

Abstract

Focusing inside scattering media is a challenging task with a variety of applications in biomedicine. State of the art methods mostly require invasive feedback inside or behind the sample, limiting practical use. We present a technique for dynamic control and focusing inside scattering media that combines two powerful methods: optical coherence tomography (OCT) and wave-front shaping (WFS). We use OCT as a non-invasive feedback for WFS optimization of a separate, penetrating laser. Energy absorbed in the sample, creates thermal expansions that are used for the feedback mechanism. By maximizing thermal deformations within a selected focal region, we demonstrate enhanced focusing of light through scattering media beyond the ballistic regime and within the penetration range of OCT.

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