Article
Single multimode fiber endoscope. Public Deposited
https://scholar.colorado.edu/concern/articles/41687j05t
- Abstract
- Multimode fibers can guide thousands of modes capable of delivering spatial information. Unfortunately, mode dispersion and coupling have so far prevented their use in endoscopic applications. To address this long-lasting challenge, we present a robust scanning fluorescence endoscope. A spatial light modulator shapes the input excitation wavefront to focus light on the distal tip of the fiber and to rapidly scan the focus over the region of interest. A detector array collects the fluorescence emission propagated back from the sample to the proximal tip of the fiber. We demonstrate that proper selection of the multimode fiber is critical for a robust calibration and for high signal-to-background ratio performance. We compare different types of multimode fibers and experimentally show that a focus created through a graded-index fiber can withstand a few millimeters of fiber distal tip translation. The resulting scanning endoscopic microscope images fluorescent samples over a field of view of 80µm with a resolution of 2µm.
- Creator
- Date Issued
- 2017-02-06
- Academic Affiliation
- Journal Title
- Journal Issue/Number
- 3
- Journal Volume
- 25
- File Extent
- 1656-1665
- Publisher
- Dernière modification
- 2019-12-05
- Identifier
- PubMed ID: 29519020
- Resource Type
- Déclaration de droits
- DOI
- ISSN
- 1094-4087
- Language
Des relations
Articles
| La vignette | Titre | Date de téléchargement | Visibilité | actes |
|---|---|---|---|---|
|
|
singleMultimodeFiberEndoscope.pdf | 2019-12-05 | Public | Télécharger |