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Submissions from 2018

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Genome-wide dose-dependent inhibition of histone deacetylases studies reveal their roles in enhancer remodeling and suppression of oncogenic super-enhancers., Gilson J Sanchez, Phillip A Richmond, Eric N Bunker, Samuel S Karman, Joseph Azofeifa, Aaron T Garnett, Quanbin Xu, Graycen E Wheeler, Cathryn M Toomey, Qinghong Zhang, Robin D Dowell, and Xuedong Liu

Submissions from 2017

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Investigating differences in DOAS retrieval codes using MAD-CAT campaign data, Theodore Koenig, Ivan Ortega, Rainer Volkamer, and See bottom of the page for full list of authors.

Submissions from 2016

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Simulating secondary organic aerosol in a regional air quality model using the statistical oxidation model – Part 2: Assessing the influence of vapor wall losses, Christopher D. Cappa, Shantanu H. Jathar, Michael J. Kleeman, Kenneth S. Docherty, Jose L. Jimenez, John H. Seinfeld, and Anthony S. Wexler

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Speciated measurements of semivolatile and intermediate volatility organic compounds (S/IVOCs) in a pine forest during BEACHON-RoMBAS 2011, A.W.H Chan, N.M. Kreisberg, T. Hohaus, Pedro Campuzano-Jost, Y. Zhao, D.A. Day, L. Kaser, T. Karl, A. Hansel, A.P. Teng, C.R. Ruehl, D.T. Sueper, J.T. Jayne, D.R. Worsnop, S.V. Hering, J.L. Jimenez, and A.H. Goldstein

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Evaluation of European air quality modelled by CAMx including the volatility basis set scheme, Giancarlo Ciarelli, Sebnem Aksoyoglu, Monica Crippa, Urs Baltensperger1, André S.H. Prévôt, Jose L. Jimenez, Eriko Nemitz, Karine Sellegri, Mikko Äijälä, Samara Carbone, Claudia Mohr, Colin O'Dowd, and Laurent Poulain

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Mercury oxidation from bromine chemistry in the free troposphere over the southeastern US, Sean Coburn, Barbara Dix, Eric Edgerton, Christopher D. Holmes, Douglas Kinnison, Qing Liang, Arnout ter Schure, Siyuan Wang, and Rainer Volkamer

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Evaluating model parameterizations of submicron aerosol scattering and absorption with in situ data from ARCTAS 2008, Michael J. Cubison, J.L. Jimenez, Matthew J. Alvarado, Chantelle R. Lonsdale, Helen L. Macintyre, and Please see bottom of the page for a full list of authors.

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Ultrafast Time-Resolved Hard X-Ray Emission Spectroscopy on a Tabletop, Niels Damrauer, Steven M. Fatur, Ralph Jimenez, Joel N. Ullom, and See full list of authors at bottom of the page.

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HMGB1 Activates Proinflammatory Signaling via TLR5 Leading to Allodynia., Nabanita Das, Varun Dewan, Peter M Grace, Robin J Gunn, Ryo Tamura, Netanel Tzarum, Linda R Watkins, Ian A Wilson, and Hang Yin

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Global impacts of tropospheric halogens (Cl, Br, I) on oxidants and composition in GEOS-Chem, Barbara Dix, Theodore K. Koenig, Roman Sinreich, Ivan Ortega, Rainer Volkamer, and Please see bottom of the page for a full list of authors.

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Parameterization retrieval of trace gas volume mixing ratios from Airborne MAX-DOAS, Barbara Dix, Theodore Koenig, and Rainer Volkamer

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Gas-phase hydrolysis of triplet SO2: A possible direct route to atmospheric acid formation., D James Donaldson, Jay A Kroll, and Veronica Vaida

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Analysis of the association between codon optimality and mRNA stability in Schizosaccharomyces pombe., Yuriko Harigaya and Roy Parker

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Rethinking the global secondary organic aerosol (SOA) budget: stronger production, faster removal, shorter lifetime, Alma Hodzic, Prasad S. Kasibhatla, Duseong S. Jo, Christopher D. Cappa, Jose L. Jimenez, Sasha Madronich, and Rokjin J. Park

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First detection of ammonia (NH3) in the Asian summer monsoon upper troposphere, Michael Höpfner, Rainer Volkamer, Udo Grabowski, Michael Grutter, Johannes Orphal, Gabriele Stiller, Thomas von Clarmann, and Gerald Wetzel

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Single molecule microscopy reveals mechanistic insight into RNA polymerase II preinitiation complex assembly and transcriptional activity., Abigail E Horn, Jennifer F Kugel, and James A Goodrich

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Aqueous-phase mechanism for secondary organic aerosol formation from isoprene: application to the southeast United States and co-benefit of SO2 emission controls, J.L. Jimenez, Pedro Campuzano-Jost, D.A. Day, W. Hu, Jordan Edward Krechmer, and Please see bottom of the page for a full list of authors.

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Organic nitrate chemistry and its implications for nitrogen budgets in an isoprene- and monoterpene-rich atmosphere: constraints from aircraft (SEAC(4)RS) and ground-based (SOAS) observations in the Southeast US, Jose L. Jimenez, Pedro Campuzano-Jost, Douglas A. Day, Weiwei Hu, and See full list of authors at bottom of the page.

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Distinct mechanisms regulating mechanical force-induced Ca2+ signals at the plasma membrane and the ER in human MSCs, Tae-Jin Kim, Chirlmin Joo, Jihye Seong, Reza Vafabakhsh, Elliot L. Botvinick, Michael W. Berns, Amy E. Palmer, Ning Wang, Taekjip Ha, Eric Jakobsson, Jie Sun, and Yingxiao Wang

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Ion mobility spectrometry-mass spectrometry (IMS-MS) for on- and offline analysis of atmospheric gas and aerosol species, Jordan Edward Krechmer, Jose L. Jimenez, Michael Groessl, Xuan Zhang, Heikki Junninen, and Please see bottom of the page for a full list of authors.

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Circular RNAs Co-Precipitate with Extracellular Vesicles: A Possible Mechanism for circRNA Clearance., Erika Lasda and Roy Parker

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Impact of chamber wall loss of gaseous organic compounds on secondary organic aerosol formation: explicit modeling of SOA formation from alkane and alkene oxidation, Y.S. La, M. Camredon, P.J. Ziemann, R. Valorso, A. Matsunaga, V. Lannuque, J. Lee-Taylor, A. Hodzic, S. Madronich, and B. Aumont

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Impacts of heterogeneous uptake of dinitrogen pentoxide and chlorine activation on ozone and reactive nitrogen partitioning: improvement and application of the WRF-Chem model in southern China, Qinyi Li, Li Zhang, Tao Wang, Yee Jun Tham, Ravan Ahmadov, Likun Xue, Qiang Zhang, and Junyu Zheng

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The Cac1 subunit of histone chaperone CAF-1 organizes CAF-1-H3/H4 architecture and tetramerizes histones., Wallace H Liu, Sarah C Roemer, Yeyun Zhou, Zih-Jie Shen, Briana K Dennehey, Jeremy L Balsbaugh, Jennifer C Liddle, Travis Nemkov, Natalie G Ahn, Kirk C Hansen, Jessica K Tyler, and Mair Ea Churchill

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Introduction: Observations and Modeling of the Green Ocean Amazon (GoAmazon2014/5), S.T. Martin, P. Artaxo, L.A.T. Machado, A.O. Manzi, R.A.F. Souza, C. Schumacher, J. Wang, M.O. Andreae, H.M.J. Barbosa, J. Fan, G. Fisch, A.H. Goldstein, A. Guenther, Jose L. Jimenez, U. Pöschl, M.A. Silva Dias, J.N. Smith, and M. Wendisch

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How Quantum Chemistry of Singlet Fission Helps to Improve the Efficiency of Solar Cells, Josef Michil

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Contribution of dissolved organic matter to submicron water-soluble organic aerosols in the marine boundary layer over the eastern equatorial Pacific, Yuzo Miyazaki, Kaori Ono, Kimitaka Kawamura, Sean Coburn, Rainer Volkamer, David T. Ho, and R. Bradley Pierce

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The CU 2-D-MAX-DOAS instrument - Part 2: Raman scattering probability measurements and retrieval of aerosol optical properties, Ivan Ortega, Sean Coburn, Larry K. Berg, Kathy Lantz, Joseph Michalsky, Richard A. Ferrare, Johnathan Hair, Chris A. Hostetler, and Rainer Volkamer

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Phase state of ambient aerosol linked with water uptake and chemical aging in the southeastern US, Aki Pajunoja, Weiwei Hu, Yu J. Leong, Nathan F. Taylor, Pasi Miettinen, Brett Brian Palm, Santtu Mikkonen, Don R. Collins, Jose L. Jimenez, and Annele Virtanen

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Heterogeneous photochemistry of imidazole-2-carboxaldehyde: HO2 radical formation and aerosol growth, Laura González Palacios, Pablo Corral Arroyo, Kifle Z. Aregahegn, Sarah S. Steimer, Thorsten Bartles-Rausch, Barbara Nozière, Christian George, Markus Ammann, and Rainer Volkamer

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In situ secondary organic aerosol formation from ambient pine forest air using an oxidation flow reactor, Brett Brian Palm, Pedro Campuzano-Jost, Amber Marie Ortega, Douglas A. Day, Lisa Kaser, Werner Jud, Thomas Karl, Armin Hansel, James F. Hunter, Eben S. Cross, Jesse H. Kroll, Zhe Peng, William H. Brune, and Jose L. Jimenez

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Non-OH chemistry in oxidation flow reactors for the study of atmospheric chemistry systematically examined by modeling, Zhe Peng, Douglas A. Day, Amber Marie Ortega, Brett Brian Palm, Weiwei Hu, Harald Stark, Rui Li, Kostas Tsigaridis, William H. Brune, and Jose L. Jimenez

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Prediction of cloud condensation nuclei activity for organic compounds using functional group contribution methods, M.D. Petters, S. M. Kreidenweis, and P.J. Ziemann

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Telomere Replication Stress Induced by POT1 Inactivation Accelerates Tumorigenesis., Alexandra M Pinzaru, Robert A Hom, Angela Beal, Aaron F Phillips, Eric Ni, Timothy Cardozo, Nidhi Nair, Jaehyuk Choi, Deborah S Wuttke, Agnel Sfeir, and Eros Lazzerini Denchi

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Mechanistic Insights into Cofactor-Dependent Coupling of RNA Folding and mRNA Transcription/Translation by a Cobalamin Riboswitch., Jacob T Polaski, Erik D Holmstrom, David J Nesbitt, and Robert T Batey

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Arginine methylation promotes translation repression activity of eIF4G-binding protein, Scd6., Gopalakrishna Poornima, Shanaya Shah, Venkadasubramanian Vignesh, Roy Parker, and Purusharth I Rajyaguru

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Identification of Mediator Kinase Substrates in Human Cells using Cortistatin A and Quantitative Phosphoproteomics, Zachary C. Poss, Christopher C. Ebmeier, Aaron T. Odell, Anupong Tangpeerachaikul, Thomas Lee, Henry E. Pelish, Matthew D. Shair, Robin D. Dowell, William M. Old, and Dylan J. Taatjes

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Comparing Residue Clusters from Thermophilic and Mesophilic Enzymes Reveals Adaptive Mechanisms., Deanne W Sammond, Noah Kastelowitz, Michael E Himmel, Hang Yin, Michael F Crowley, and Yannick J Bomble

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Iodine's impact on tropospheric oxidants: a global model study in GEOS-Chem, T. Sherwen, M.J. Evans, L.J. Carpenter, S.J. Andrews, R.T. Lidster, B. Dix, T.K. Koenig, R. Sinreich, Ivan Ortega, Rainer Volkamer, A. Saiz-Lopez, C. Prados-Roman, A.S. Mahajan, and C. Ordóñez

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Distinct stages in stress granule assembly and disassembly., Joshua R Wheeler, Tyler Matheny, Saumya Jain, Robert Abrisch, and Roy Parker

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A quantitative investigation of linker histone interactions with nucleosomes and chromatin., Alison E White, Aaron R Hieb, and Karolin Luger

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Organic and inorganic decomposition products from the thermal desorption of atmospheric particles, Brent J. Williams, Yaping Zhang, Xiaochen Zuo, Raul E. Martinez, Michael J. Walker, Nathan M. Kreisberg, Allen H. Goldstein, Kenneth S. Docherty, and Jose L. Jimenez

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Understanding sources of organic aerosol during CalNex-2010 using the CMAQ-VBS, Matthew C. Woody, Kirk R. Baker, Patrick L. Hayes, Jose L. Jimenez, Bonyoung Koo, and Havala O.T. Pye

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Aircraft-measured indirect cloud effects from biomass burning smoke in the Arctic and subarctic, L.M. Zamora, R.A. Kahn, Michael J. Cubison, G.S. Diskin, J.L. Jimenez, Y. Kondo, G.M. McFarquhar, A. Nenes, K.L. Thornhill, A. Wisthaler, A. Zelenyuk, and L.D. Ziemba

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Mps1 kinase regulates tumor cell viability via its novel role in mitochondria., X Zhang, Y Ling, Y Guo, Y Bai, X Shi, F Gong, P Tan, Y Zhang, C Wei, X He, A Ramirez, X Liu, C Cao, H Zhong, Q Xu, and R Z Ma

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A novel framework for molecular characterization of atmospherically relevant organic compounds based on collision cross section and mass-to-charge ratio, Xuan Zhang, Michael Groessl, Jordan Edward Krechmer, Wen Xu, John T. Jayne, Douglas R. Worsnop, Manjula R. Canagaratna, Stephan Graf, Michael J. Cubison, and Jose L. Jimenez

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A technique for rapid source apportionment applied to ambient organic aerosol measurements from a thermal desorption aerosol gas chromatograph (TAG), Yaping Zhang, Brent J. Williams, Allen H. Goldstein, Kenneth S. Docherty, and Jose L. Jimenez

Submissions from 2015

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Modeling the formation and aging of secondary organic aerosols in Los Angeles during CalNex 2010, Ravan Ahmadov, P.L. Hayes, A.G. Carlton, K.R. Baker, R.A. Washenfelder, S. Alvarez, B. Rappenglück, J.B. Gilman, W.C. Kuster, A.S.H. Prévôt, J.A. de Gouw, S. Szidat, T.E. Kleindienst, J.H. Offenberg, P.K. Ma, and J.L. Jimenez

Understanding high wintertime ozone pollution events in an oil- and natural gas-producing region of the western US, Ravan Ahmadov, S. McKeen, M. Trainer, R Banta, A Brewer, S. Brown, P.M. Edwards, J.A. de Gouw, G.J. Frost, J. Gilman, D. Helmig, B. Johnson, A. Karion, A. Koss, A. Langford, B. Lerner, J. Olson, S. Oltmans, J. Peischl, G. Pétron, Y. Pichugina, J.M. Roberts, T. Ryerson, R. Schnell, C. Senff, C. Sweeney, C. Thompson, P.R. Veres, C. Warneke, R. Wild, E.J. Williams, B. Yuan, and R. Zamora

Submissions from 2014

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Structure and Function of Steroid Receptor RNA Activator Protein, the Proposed partner of SRA noncoding RNA, David B. McKay, Linghe Xi, Kristen K.B. Barthel, and Thomas R. Cech

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Telomerase in Bladder Cancer: Back to a Better Future?, Dan Theodorescu

Submissions from 2013

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RNA Recognition by the DNA End-Binding Ku Heterodimer, Andrew B. Dalby, Karen J. Goodrich, Jennifer S. Pfingsten, and Thomas R. Cech

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3' Terminal Diversity of MRP RNA and Other Human Noncoding RNAs Revealed by Deep Sequencing, Katherine C. Goldfarb and Thomas R. Cech

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RNA Seeds Higher-Order Assembly of FUS Protein, Jacob V. Schwartz, Xueyin Wang, Elaine R. Podell, and Thomas R. Cech

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Many Disease-Associated Variants of hTERT Retain High Telomerase Enzymatic Activity, Arthur J. Zaug, Sharon M. Crary, Matthew Jesse Fioravanti, Kristina Campbell, and Thomas R. Cech

Submissions from 2012

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RNase P Branches Out from RNP to Protein: Organelle-Triggered Diversification?, Katherine C. Goldfarb, Sumit Borah, and Thomas R. Cech

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DNA-induced Dimerization of the Single-Stranded DNA Binding Telomeric Protein Pot1 from Schizosaccharomyces Pombe, Jayakrishnan Nandakumar and Thomas R. Cech

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Reduction of Metal Ions by Boranephosphonate DNA, Subhadeeo Roy, Magdalena Olesiak, Petra Padar, Heather Brummel McCuen, and Marvin H. Caruthers

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FUS Binds the CTD of RNA Polymerase II and Regulates its Phosphorylation at Ser2, Jacob C. Schwartz, Christopher C. Ebmeier, Elaine R. Podell, Joseph Heimiller, Dylan J. Taatjes, and Thomas R. Cech

Submissions from 2011

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Multiple POT1–TPP1 Proteins Coat and Compact Long Telomeric Single-Stranded DNA, Derek J. Taylor, Elaine R. Podell, Dylan J. Taatjes, and Thomas R. Cech

Submissions from 2010

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Tetrahymena Telomerase Protein p65 Induces Conformational Changes throughout Telomerase RNA (TER) and Rescues Telomerase Reverse Transcriptase and TER Assembly Mutants▿†, Andrea J. Berman, Anne R. Gooding, and Thomas R. Cech

Synthesis of High-Quality Libraries of Long (150 mer) Oligonucleotides by a Novel Depurination Controlled Process, Emily M. LeProust, Bill J. Peck, Konstantin Spirin, Heather Brummel McCuen, Bridget Moor, Eugeni Namsaraev, and Marvin H. Caruthers

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Ku Can Contribute to Telomere Lengthening in Yeast at Multiple Positions in the Telomerase RNP, David C. Zappulla, Karen J. Goodrich, Julian R. Arthur, Lisa A. Gurski, Elizabeth M. Denham, Anne E. Stellwagen, and Thomas R. Cech

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Functional Interaction Between Telomere Protein TPP1 and Telomerase, Arthur J. Zaug, Elaine R. Podell, Jayakrishnan Nandakumar, and Thomas R. Cech

Submissions from 2009

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Translational Careers, Nancy Andrew, John E. Burris, Thomas R. Cech, Barry S. Coller, William F. Crowley Jr., Elaine K. Gallin, Katrina L. Kglner, Darrell G. Kirch, Alan I. Leshner, Cynthia D. Morris, Freddy T. Nguyen, Jim Oates, and Nancy S. Sung

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Crawling Out of the RNA World, Thomas R. Cech

Submissions from 2008

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Multiple Yeast Genes, Including Paf1 Complex Genes, Affect Telomere Length via Telomerase RNA Abundance, Amy D. Mozdy, Elaine R. Podell, and Thomas R. Cech

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Toward Predicting Self-Splicing and Protein-Facilitated Splicing of Group I Introns, Quentin Vicens, Paul J. Paukstelis, Eric Westhof, Alan M. Lambowitz, and Thomas R. Cech

Inhibition of Yeast Telomerase Action by the Telomeric ssDNA-binding Protein, Cdc13p, David C. Zappulla, Jennifer N. Roberts, Karen J. Goodrich, Thomas R. Cech, and Deborah S. Wuttke

Submissions from 2007

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Local RNA Structural Changes Induced by Crystallization are Revealed by SHAPE, Quentin Vicens, Anna R. Gooding, Alain Laederach, and Thomas R. Cech

Submissions from 2006

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Comparison of Crystal Structure Interactions and Thermodynamics for Stabilizing Mutations in the Tetrahymena Ribozyme, Feng Guo, Anne R. Gooding, and Thomas R. Cech

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Low Abundance of Telomerase in Yeast: Implications for Telomerase Haploinsufficiency, Amy D. Mozdy and Thomas R. Cech

Submissions from 2004

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The Euplotes Telomerase Subunit p43 Stimulates Enzymatic Activity and Processivity in vitro, Stefan Aigner and Thomas R. Cech

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Beginning to Understand the End of the Chromosome, Thomas R. Cech

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Global Expression Changes Resulting from Loss of Telomeric DNA in Fission Yeast, Jeffrey G. Mandell, Jürg Bähler, Thomas A. Volpe, Robert A. Martienssen, and Thomas R. Cech

Submissions from 2003

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Tetrahymena Telomerase is Active as a Monomer, Tracy M. Bryan, Karen J. Goodrich, and Thomas R. Cech

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Yeast Telomerase is Specialized for C/A-rich RNA Templates, Klaus Förstemann, Arthur J. Zaug, Thomas R. Cech, and Joachim Lingner

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N-terminal Domain of Yeast Telomerase Reverse Transcriptase: Recruitment of Est3p to the Telomerase Complex, Katherine L. Friedman, Jeremy J. Heit, David M. Long, and Thomas R. Cech

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A Template-proximal RNA Paired Element Contributes to S. cerevisiae Telomerase Activity, Anita G. Seto, Kfir Umansky, Yehuda Tzfati, Arthur J. Zaug, Elizabeth H. Blackburn, and Thomas R. Cech

Submissions from 2002

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Human Pot1 (Protection of Telomeres) Protein: Cytolocalization Gene Structure, and Alternative Splicing, Peter Baumann, Elaine Podell, and Thomas R. Cech

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In vivo Selection of Better Self-Splicing Introns in E. coli: the Role of the P1 Extension Helix of the Tetrahymena Intron, Feng Guo and Thomas R. Cech

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A Bulged Stem Tethers Est1p to Telomerase RNA in Budding Yeast, Anita G. Seto, April J. Livengood, Yehuda Tzfati, Elizabeth H. Blackburn, and Thomas R. Cech

Submissions from 2001

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Pot1, the Putative Telomere End-binding Protein in Fission Yeast and Humans, Peter Baumann and Thomas R. Cech

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An Early Transition State for Folding of the P4-P6 RNA Domain., Scott K. Silverman and Thomas R. Cech

Submissions from 2000

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Protection of Telomeres by the Ku Protein in Fission Yeast, Peter Baumann and Thomas R. Cech

Structural biology. The Ribosome is a Ribozyme, Thomas R. Cech