Document Type

Article

Publication Date

Spring 5-15-2012

Publication Title

Genes and Development

Volume

26

First Page

1005

Last Page

1009

DOI

10.1101/gad.193581.112

Abstract

RNase P is the enzyme that removes 5′ leader sequences from precursor tRNAs. Remarkably, in most organisms, RNase P is a ribonucleoprotein particle where the RNA component is responsible for catalysis. In this issue of Genes & Development, Gutmann and colleagues (pp. 1022–1027) report the first organism,Arabidopsis thaliana, to employ protein-only RNase P in both its nucleus and organelles. An intriguing possibility is that replacement of RNase P ribonucleoprotein particles (RNPs) by proteins may have been triggered by the acquisition of organelles.

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